RELA, RELA proto-oncogene, NF-kB subunit, 5970

N. diseases: 483; N. variants: 11
Disease: Pancreatic Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 Biomarker disease BEFREE This study aimed to investigate whether downregulation of the p65 subunit of NF-kappaB by siRNA could enhance the efficacy of gemcitabine to treat pancreatic cancer. p65 siRNA synergized with gemcitabine to inhibit the proliferation and induce the apoptosis of pancreatic cancer cells in vitro and in vivo, and suppress the growth and angiogenesis of pancreatic tumors in nude mice. 19880242 2010
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 AlteredExpression disease LHGDN Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. 12618762 2003
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 AlteredExpression disease LHGDN Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer. 12767057 2003