REN, renin, 5972

N. diseases: 721; N. variants: 25
Disease: Keloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022548
Disease: Keloid
Keloid 		0.030 Biomarker disease BEFREE We have previously shown an embryonic stem cell (ESC)-like population within keloid-associated lymphoid tissues (KALTs) in keloid lesions (KLs) expresses components of the renin-angiotensin system (RAS) which maybe dysregulated. 31524804 2019
CUI: C0022548
Disease: Keloid
Keloid 		0.030 Biomarker disease BEFREE Cathepsins B, D, and G are expressed by the embryonic stem cell-like population within the keloid-associated lymphoid tissues of keloid lesions and may act to bypass the renin-angiotensin system, suggesting a potential therapeutic target using renin-angiotensin system modulators and cathepsin inhibitors. 31764649 2019
CUI: C0022548
Disease: Keloid
Keloid 		0.030 Biomarker disease BEFREE However, the role of chymase in the local renin-angiotensin system (RAS) in keloids has not been elucidated. 26357464 2015