REN, renin, 5972

N. diseases: 721; N. variants: 25
Disease: Acute pulmonary embolism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2882221
Disease: Acute pulmonary embolism
Acute pulmonary embolism 		0.020 GeneticVariation disease BEFREE A recent study by our group discovered a post‑resuscitation imbalance in the serum angiotensin‑converting enzyme (ACE)2/ACE axis of the renin‑angiotensin system (RAS), as well as regressive cardiac function in a porcine model of APE‑CA. 30816437 2019
CUI: C2882221
Disease: Acute pulmonary embolism
Acute pulmonary embolism 		0.020 GeneticVariation disease BEFREE Although the anatomical obstruction of the pulmonary vascular bed initiates APE, recent studies have suggested that vasoconstrictors in the renin-angiotensin system (RAS) play a role in the severity of APE. 30784777 2019