REN, renin, 5972

N. diseases: 721; N. variants: 25
Disease: Malignant neoplasm of colon and/or rectum ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.040 GeneticVariation disease BEFREE We performed a meta-analysis to investigate the correlation between renin-angiotensin system gene polymorphisms and colorectal cancer. 31642377 2020
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.040 AlteredExpression disease BEFREE The renin-angiotensin system (RAS) is upregulated in colorectal cancer, and epidemiologic studies suggest RAS inhibitors reduce cancer risk. 31088824 2019
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.040 Biomarker disease BEFREE Renin-Angiotensin-Aldosterone System-based Antihypertensive Agents and the Risk of Colorectal Cancer Among Medicare Beneficiaries. 31348009 2019
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.040 Biomarker disease BEFREE Relationship between drugs affecting the renin-angiotensin system and colorectal cancer: The MCC-Spain study. 28131779 2017