RET, ret proto-oncogene, 5979

N. diseases: 607; N. variants: 162
Disease: Congenital anomaly of the kidney ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0266292
Disease: Congenital anomaly of the kidney
Congenital anomaly of the kidney 		0.030 GeneticVariation group BEFREE These data suggest that in humans, mutations in RET and GDNF may contribute significantly to abnormal kidney development. 18252215 2008
CUI: C0266292
Disease: Congenital anomaly of the kidney
Congenital anomaly of the kidney 		0.030 GeneticVariation group BEFREE Although kidney agenesis or dysgenesis has been observed in mice lacking functional ret, no clinically relevant kidney abnormalities have been reported in individuals with known RET mutations and familial medullary thyroid carcinoma (FMTC). 11454140 2001
CUI: C0266292
Disease: Congenital anomaly of the kidney
Congenital anomaly of the kidney 		0.030 AlteredExpression group BEFREE Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice. 10023663 1999