RET, ret proto-oncogene, 5979

N. diseases: 607; N. variants: 162
Disease: Histiocytic syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0398597
Disease: Histiocytic syndrome
Histiocytic syndrome 		0.010 Biomarker disease BEFREE In this study, we uncovered activating mutations in CSF1R and rearrangements in RET and ALK that conferred dramatic responses to selective inhibition of RET (selpercatinib) and crizotinib, respectively, in patients with histiocytosis. 31768065 2019