Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE These results demonstrate a previously unrecognized relationship between p53 and REV3L in cancer cell metabolism and may lead to improvements in chemotherapy treatment plans that reduce cisplatin resistance in lung cancer. 29307819 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE Taken together, we demonstrated that inhibition of REV3L sensitized lung cancer H1299 cells to cisplatin treatment. 26165320 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 GeneticVariation disease BEFREE To investigate association between REV3L polymorphisms and lung cancer risk in a Chinese population, we first genotyped 15 common polymorphisms of the REV3L gene and found that three single nucleotide polymorphisms (rs465646, rs459809 and rs1002481) were significantly associated with lung cancer risk. 22349819 2013