TRIM27, tripartite motif containing 27, 5987

N. diseases: 90; N. variants: 3
Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 Biomarker group BEFREE The luminescence tracking properties of Eu<sup>3+</sup>-doped (red emission) and Tb<sup>3+</sup>-doped (green emission) NPs were successfully characterized by co-encapsulating with genetically modified cancer cell lines expressing green or red fluorescent proteins (GFP and RFP) in addition to a mixed population of live and dead cells stained with ethidium homodimer. 30483856 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE RET finger protein (RFP) is a protein that is expressed in many kinds of cancer.RFP forms a protein complex with HDAC1. 31178471 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 Biomarker group BEFREE Tripartite motif‑containing 27 (TRIM27) belongs to the tripartite motif (TRIM) protein family and is involved in various malignant tumor processes. 29767249 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE However, the significance of RFP expression in cancer patients remains elusive. 23342271 2012
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE RFP is expressed in a variety of human and rodent tumor cell lines and in several kinds of human cancer. 22524660 2012
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 GeneticVariation group BEFREE The contribution of RB1 on senescence and cancer susceptibility (n > 20 mice per group) in Trim27(-/-) backgrounds was also assessed. 22556269 2012
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 Biomarker group BEFREE Accordingly, RNA interference-mediated depletion of RFP led to the disruption of the protein complex and a marked increase in the sensitivity of cancer cells to cisplatin, a potent inducer of oxidative stress. 19351825 2009