BCL2L2, BCL2 like 2, 599

N. diseases: 66; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung
0.020 Biomarker disease BEFREE ABT-737, a small-molecule BH3-mimetic, selectively inhibits BCL-2, BCL-XL, and BCL-w and shows promise for treating leukemia, lymphoma, and small-cell lung cancer. 22173547 2012
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung
0.020 Biomarker disease BEFREE Additional highly localized DNA amplifications suggested candidate oncogenes not previously identified as amplified in SCLC, including the antiapoptotic genes TNFRSF4 (1p36), DAD1 (14q11), BCL2L1 (20q11) and BCL2L2 (14q11). 16116477 2006