ACTB, actin beta, 60

N. diseases: 1110; N. variants: 39
Disease: acute flaccid myelitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4290000
Disease: acute flaccid myelitis
acute flaccid myelitis 		0.010 Biomarker disease BEFREE Here, using genome-scale CRISPR screens, we identify the actin histidine methyltransferase SET domain containing 3 (SETD3) as critically important for viral infection by a broad panel of EVs, including rhinoviruses and non-polio EVs increasingly linked to severe neurological disease such as acute flaccid myelitis (EV-D68) and viral encephalitis (EV-A71). 31527793 2019