BCL6, BCL6 transcription repressor, 604

N. diseases: 309; N. variants: 3
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.010 AlteredExpression disease BEFREE RORγt in T cells is required for optimal T<sub>H</sub>2 cell differentiation by suppressing Bcl6 expression; this finding suggests that targeting RORγt might be a promising approach for the treatment of allergic asthma by concomitantly suppressing T<sub>H</sub>17 and T<sub>H</sub>2 cell responses in the airway. 28943467 2018