BCL6, BCL6 transcription repressor, 604

N. diseases: 309; N. variants: 3
Disease: Mediastinal (Thymic) Large B-Cell Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1292754
Disease: Mediastinal (Thymic) Large B-Cell Lymphoma
Mediastinal (Thymic) Large B-Cell Lymphoma 		0.310 Biomarker disease BEFREE "Double-hit" (DH) lymphomas are B-cell neoplasms characterized by a translocation involving MYC and either BCL2 or BCL6 In the indexed literature, there are no reported cases of PMLBCL associated with DH or triple-hit events. 27124935 2016
CUI: C1292754
Disease: Mediastinal (Thymic) Large B-Cell Lymphoma
Mediastinal (Thymic) Large B-Cell Lymphoma 		0.310 SomaticCausalMutation disease ORPHANET Intravascular large B-cell lymphoma associated with a near-tetraploid karyotype, rearrangement of BCL6, and a t(11;14)(q13;q32). 17116487 2006