Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.010 AlteredExpression disease BEFREE To investigate whether the JAK-STAT (Janus kinase-signal transducers and activators of transcription) pathway participates in the regulation of APOBEC3G (Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) gene transcription and to study the molecular mechanisms of interferon resistance in patients with chronic hepatitis B (CHB), changes in APOBEC3G and STAT-1 expression levels in HepG2.2.15 cells after treatment with various concentrations of IFN-α, were detected using real-time RT-PCR and Western-blot. 20957108 2010