RORC, RAR related orphan receptor C, 6097

N. diseases: 88; N. variants: 6
Disease: Arthritis, Psoriatic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic 		0.010 Biomarker disease BEFREE TCRβ sequencing showed these cells are polyclonal in PsA (median clonality = 0.08), whilst RNA-seq and deep-immunophenotyping revealed that PsA synovial Tc17 cells have hallmarks of Th17 (RORC/IL23R/CCR6/CD161) and Tc1 cells (granzyme A/B). 31677365 2020