RORC, RAR related orphan receptor C, 6097

N. diseases: 88; N. variants: 6
Disease: High Grade Sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1334008
Disease: High Grade Sarcoma
High Grade Sarcoma 		0.010 Biomarker disease BEFREE We thus demonstrated that in DFSP evolution to high grade sarcoma, EGFR and SNAIL were involved, with EGFR activation and signaling through TOR and STAT5a/b downstream effectors, which could lead on to new therapies for advanced DFSP. 29492209 2018