RPE, ribulose-5-phosphate-3-epimerase, 6120

N. diseases: 90; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.030 Biomarker disease BEFREE In conclusion, data have suggested that PACAP-38 acts through EGFR phosphorylation in DR and this effect particularly occurs on RPE layer. 31247223 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.030 Biomarker disease BEFREE Presently, we aimed to evaluate the possible role of the DOR on the maintenance of tight junction of RPE layer and on the early markers of experimental DR. 31529081 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.030 GeneticVariation disease BEFREE There were also increased iron levels within the RPE of retinal sections from a patient with MacTel2 and both RPE and neurosensory retina of a patient with diabetic retinopathy, which, like MacTel2, causes retinal vascular leakage. 28846772 2017