RPS6, ribosomal protein S6, 6194

N. diseases: 117; N. variants: 2
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.030 Biomarker disease BEFREE In this retrospective analysis of treatment-naïve samples of the OSAG 101-BSA-05 trial cohort, we identify the EGFR signaling activity markers phosphorylated PRAS40 and phosphorylated ribosomal protein S6 as predictive markers for treatment efficacy of the EGFR-blocking antibody nimotuzumab in MGMT promoter unmethylated GBs. 30129426 2018
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.030 Biomarker disease BEFREE Our results suggest that mTOR and rpS6 could be used as markers of overactivation of the PI3K-mTOR pathway and are predictive factors for overall survival in glioblastomas. 29328863 2018
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.030 Biomarker disease BEFREE Knockdown of CPE leads to a decrease of active RPS6 associated with increased GBM cell motility. 28978054 2017