BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Cocaine Abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease BEFREE For several decades, BDNF has been implicated in mediating synaptic plasticity associated with cocaine abuse, and most studies report that neurons are the primary source for BDNF production in the brain. 29859319 2018
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185 2010
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. 20810894 2010
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. 20810894 2010
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185 2010
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. 19321768 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. 19321768 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559 2008
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559 2008
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. 17618281 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats. 17651427 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats. 17651427 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. 17618281 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. 14973246 2004
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic disease CTD_human A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. 14973246 2004