BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		0.050 Biomarker disease BEFREE Finally, it was found that sophoridine suppresses the protein expression of FoxM1, TrkB, BDNF NF-κB and AP-1 in human medulloblastoma cells. 29344238 2017
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		0.050 Biomarker disease BEFREE BDNF/TrkB Signaling as a Potential Novel Target in Pediatric Brain Tumors: Anticancer Activity of Selective TrkB Inhibition in Medulloblastoma Cells. 26614346 2016
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		0.050 Biomarker disease BEFREE In the present study, we have examined the influence of brain-derived neurotrophic factor (BDNF)/TrkB receptor- and gastrin-releasing peptide receptor (GRPR)-mediated signaling on the viability of human medulloblastoma cells. 19642024 2010
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		0.050 Biomarker disease BEFREE NT acts through two groups of structurally unrelated neurotrophin receptors (NTR): a family of receptor tyrosine kinases (Trks, mainly TrkA, TrkB, and TrkC) and a tumor necrosis factor receptor (TNFR)-like molecule called p75NTR TrkC expression is a good prognostic indicator for MB. 17550129 2007
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		0.050 AlteredExpression disease BEFREE Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. 7809137 1994