BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Plaque, Amyloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid 		0.020 Biomarker disease BEFREE The BDNF-secreting Aβ-T cells migrated efficiently to amyloid plaques, where they significantly increased the levels of BDNF, its receptor TrkB, and various synaptic proteins known to be reduced in AD. 31085101 2019
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid 		0.020 Biomarker disease BEFREE Immunohistological studies revealed increased BDNF immunoreactivity around amyloid plaques indicating that the plaques may sequester BDNF protein and prevent it from activating TrkB. 23844236 2013