BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Epileptic Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Biomarker phenotype BEFREE Several members of flavonoid family have also showed suppression of epileptic seizures via interaction with CREB/BDNF pathway. 31400269 2019
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 AlteredExpression phenotype BEFREE We aimed to determine whether a common polymorphism of the brain-derived neurotrophic factor (BDNF), which constitutes an important and ubiquitously expressed neurotrophine in the brain, affects the stimulation threshold of ECTs required to induce an epileptic seizure over time. 27787610 2017
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Therapeutic phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Biomarker phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Biomarker phenotype BEFREE We assessed plasma [corrected] BDNF immunoreactivity in 15 patients with ES, 12 patients with PNES, and 17 healthy volunteers. 20921514 2010
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Therapeutic phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Therapeutic phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.330 Biomarker phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997