SORT1, sortilin 1, 6272

N. diseases: 111; N. variants: 8
Disease: Cholelithiasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008350
Disease: Cholelithiasis
Cholelithiasis 		0.010 Biomarker disease BEFREE Consistently, high cholesterol atherogenic diet-challenged Sort1 knock-out mice showed less hepatic free cholesterol accumulation, increased bile acid synthesis, decreased biliary cholesterol secretion, and the absence of gallstone formation. 27881673 2017