SORT1, sortilin 1, 6272

N. diseases: 111; N. variants: 8
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 Biomarker group BEFREE Thus, an overview of several roles ascribed to sortilin in diabetes and other metabolic diseases are presented. 30697159 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 AlteredExpression group BEFREE In addition, the receiver operating characteristic curve analysis showed that plasma sortilin levels could identify the presence of CAD or diabetes mellitus. 28728579 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 Biomarker group BEFREE We suggest that sortilin- and retromer-mediated Glut4 retrieval from endosomes may represent a step in the Glut4 pathway vulnerable to the development of insulin resistance and diabetes. 28450454 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 AlteredExpression group BEFREE In summary, therapeutic strategies that prevent posttranslational hepatic Sort1 down-regulation in obesity and diabetes may be beneficial in improving dyslipidemia. 24986865 2014
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 Biomarker group BEFREE This study investigated the regulation of hepatic Sort1 in obesity and diabetes and the potential implications in diabetic dyslipidemia. 23904453 2013