SORT1, sortilin 1, 6272

N. diseases: 111; N. variants: 8
Disease: Hyperlipidemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.030 Biomarker disease BEFREE Sortilin is closely associated with hyperlipidemia and the risk of atherosclerosis (AS). 30950489 2019
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.030 Biomarker disease BEFREE We developed Sort1 floxed mice and investigated the development of Western diet (WD)-induced steatosis, hepatic inflammatory response, and hyperlipidemia in hepatocyte Sort1 KO mice and myeloid cell Sort1 KO mice. 30670473 2019
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.030 Biomarker disease BEFREE Sortilin deficiency is caused by accelerated proteasome degradation under insulin resistance conditions and is thereby implicated in the hyperlipidemia of type 2 diabetes mellitus (T2DM). 28945101 2017