SORT1, sortilin 1, 6272

N. diseases: 111; N. variants: 8
Disease: Dyslipidemias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.030 Biomarker group BEFREE Sortilin, encoded by the dyslipidemia-related gene SORT1, is also an important regulator of lipoprotein metabolism. 27846466 2017
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.030 AlteredExpression group BEFREE In summary, therapeutic strategies that prevent posttranslational hepatic Sort1 down-regulation in obesity and diabetes may be beneficial in improving dyslipidemia. 24986865 2014
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.030 Biomarker group BEFREE These results suggest that increased saturated fatty acids downregulate liver Sort1 protein, which may contribute to the development of dyslipidemia in obesity and diabetes. 23904453 2013