S100A7, S100 calcium binding protein A7, 6278

N. diseases: 119; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE The S100 calcium-binding protein A7 (S100A7) has been shown to promote cell proliferation, migration, invasion, and tumor metastasis. 29485916 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Increasing psoriasin expression in GC cell lines promoted cell proliferation, migration and invasion in vitro. 29956751 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE Furthermore, S100A7 was found to be secreted into the conditioned media and extracellular S100A7 enhanced cell migration and invasion. 28212564 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE As such, the proposed implications of Psoriasin in invasion, disease progression and as a potential therapeutic target warrant further investigation. 28393239 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Also, the downregulation of S100A7 expression by RNA interference-mediated silencing inhibits oral cancer cell growth, migration and invasion. 27767088 2016
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Down-regulation of S100A7 could be an effective approach for the down-regulation and inactivation of NF-κB and its target genes, such as MMP-9 and VEGF expression, resulting in the inhibition of invasion and growth. 23618129 2013
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE Psoriasin (S100A7) is a positive regulator of survival and invasion of prostate cancer cells. 22694938 2013
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Here, we show that down-regulation of endogenous psoriasin expression via stable short hairpin RNAs in a human IBC cell line (MDA-MB-468) increases cell migration and invasion without influencing cell proliferation and survival in vitro but inhibits tumor growth in vivo. 16357139 2005