|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Knockdown of S100A7 significantly suppressed ASC-stimulated cell proliferation and migration rate, indicating a possible involvement of S100A7 in the carcinoma-ASC interaction in breast tumors.
|
28629450 |
2017 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In summary, our work used a powerful new model system to show that S100A7 enhances breast tumor growth and metastasis by activating proinflammatory and metastatic pathways.
|
22158945 |
2012 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
This association was confirmed using publicly available microarray data from an independent breast tumor cohort (n=201, P=0.0005) and a correlation between S100A7 and poor patient survival was observed specifically in cases with high OSMRbeta expression (HR=2.35; P=0.0396; n=85).
|
20101226 |
2010 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
LHGDN |
S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.
|
18320059 |
2008 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These results are consistent with a role for S100A7 in modulating the immune response which may be a factor in early breast tumor progression.
|
17560571 |
2007 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
LHGDN |
These results are consistent with a role for S100A7 in modulating the immune response which may be a factor in early breast tumor progression.
|
17560571 |
2007 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A relationship between ERbeta and psoriasin/S100A7 was observed in the p53 immunohistochemically negative subset of invasive breast tumors in-vivo (r = 0.225, p = 0.046, n = 79).
|
17009105 |
2007 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
S100A7 and phospho-Akt are also correlated in breast tumors examined by immunohistochemistry (n = 142; P < 0.0001; r = 0.34).
|
15994944 |
2005 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Based on these results, we propose that psoriasin may play a role in breast tumor progression by promoting angiogenesis and enhancing the selection for cells that overcome its anti-invasive function.
|
16357139 |
2005 |
|
Mammary Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Based on these results, we propose that psoriasin may play a role in breast tumor progression by promoting angiogenesis and enhancing the selection for cells that overcome its anti-invasive function.
|
16357139 |
2005 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Molecular analysis of breast tumors has revealed that several S100s, including S100A2, S100A4 and S100A7, exhibit altered expression levels during breast tumorigenesis and/or progression.
|
15217486 |
2004 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Quantitative analysis of psoriasin mRNA has shown that breast tumour tissues exhibited a significantly high level of psoriasin compared with normal tissues (p=0.0026).
|
15201992 |
2004 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Quantitative analysis of psoriasin mRNA has shown that breast tumour tissues exhibited a significantly high level of psoriasin compared with normal tissues (p=0.0026).
|
15201992 |
2004 |
|
Mammary Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In the present study we have sought to identify potential psoriasin-binding proteins and to describe their expression profile in breast tumors.
|
12421467 |
2002 |