|
Malignant tumor of colon
|
0.340 |
Biomarker
|
disease |
BEFREE |
We propose that NOX1-dependent mTORC1 activation via S100A9 oxidation in VPS41-/VPS39-positive lysosomes is crucial for colon CSC proliferation and colon cancer progression.
|
31365870 |
2019 |
|
Malignant tumor of colon
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
It is found that S100A9, is highly expressed in G-MDSC-derived exosomes, and its blockade suppresses CRC cell stemness and the susceptibility of mice to AOM/DSS-induced colitis-associated colon cancer.
|
31559140 |
2019 |
|
Malignant tumor of colon
|
0.340 |
Biomarker
|
disease |
BEFREE |
We previously revealed that S100a8 and S100a9 are highly activated and play an important role in the process of colitis-associated carcinogenesis, which suggests an attractive therapeutic target for ulcerative colitis and related colon cancer.
|
29326691 |
2017 |
|
Malignant tumor of colon
|
0.340 |
Biomarker
|
disease |
BEFREE |
The present study aimed to identify proteins that interact with calgranulin B to suppress the proliferation of colon cancer cells, and to obtain information on the underlying anti-tumor mechanism(s) of calgranulin B. Calgranulin B expression was induced in colon cancer cell line HCT-116 by infection with calgranulin B-FLAG expressing lentivirus, and it led to a significant suppression of cell proliferation.
|
28036279 |
2017 |
|
Malignant tumor of colon
|
0.340 |
Biomarker
|
disease |
CTD_human |
Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
|
15059925 |
2004 |
|
Schizophrenia
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
This study used a rat model to test whether prenatal immune activation with lipopolysaccharide (LPS; at gestation days, GD, 15 and 16) or maternal iron deficiency (from GD2 to postnatal day P7) or the combination of both insults alters major subtypes of GABAergic interneurons (parvalbumin, somatostatin, cholecystokinin) in brain regions relevant to schizophrenia (medial and dorsolateral prefrontal cortex [PFC], hippocampal CA1 and dentate gyrus, ventral subiculum) in offspring at P14 or P28.
|
28214898 |
2016 |
|
Schizophrenia
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Linear and non-linear combinations of eight putative biomarker genes (APOBEC3B, ADSS, ATM, CLC, CTBP1, DATF1, CXCL1, and S100A9) were able to discriminate between schizophrenia, BPD, and control samples, with an overall accuracy of 95%-97% as indicated by receiver operating characteristic (ROC) curve analysis.
|
15645418 |
2005 |
|
Celiac Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
Celiac disease biomarkers identified by transcriptome analysis of small intestinal biopsies.
|
30097691 |
2018 |
|
Liver Cirrhosis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Systems level analysis and identification of pathways and networks associated with liver fibrosis.
|
25380136 |
2014 |
|
Respiratory Distress Syndrome, Adult
|
0.300 |
Biomarker
|
disease |
CTD_human |
MicroRNA and mRNA expression profiling in rat acute respiratory distress syndrome.
|
25070658 |
2014 |
|
Keloid
|
0.300 |
Biomarker
|
disease |
CTD_human |
Comparative proteomic analysis between normal skin and keloid scar.
|
20128793 |
2010 |
|
Colonic Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
|
15059925 |
2004 |
|
Malignant neoplasm of urinary bladder
|
0.230 |
Biomarker
|
disease |
BEFREE |
In this immunohistochemical study we evaluated the predictive roles of three immunological markers, CD68, MAC387, and CLEVER-1, in response to NAC and outcome of BC.
|
28978923 |
2017 |
|
Malignant neoplasm of urinary bladder
|
0.230 |
AlteredExpression
|
disease |
BEFREE |
In this study, our aim was to determine the levels of S100A8 and S100A9 in the sera, and calprotectin levels in the sera and urines of bladder cancer patients and compare it to urinary BTA, a tumor marker that can be used in the diagnosis of bladder cancer.
|
28609200 |
2017 |
|
Bladder Neoplasm
|
0.230 |
Biomarker
|
disease |
BEFREE |
In this immunohistochemical study we evaluated the predictive roles of three immunological markers, CD68, MAC387, and CLEVER-1, in response to NAC and outcome of BC.
|
28978923 |
2017 |
|
Bladder Neoplasm
|
0.230 |
AlteredExpression
|
disease |
BEFREE |
In this study, our aim was to determine the levels of S100A8 and S100A9 in the sera, and calprotectin levels in the sera and urines of bladder cancer patients and compare it to urinary BTA, a tumor marker that can be used in the diagnosis of bladder cancer.
|
28609200 |
2017 |
|
Malignant neoplasm of urinary bladder
|
0.230 |
PosttranslationalModification
|
disease |
BEFREE |
p14 hypermethylation could be involved in early stage of bladder carcinogenesis, and p14 hypermethylation in pathologically normal urothelium samples should be considered a predictor of bladder cancer recurrence.
|
20800513 |
2012 |
|
Bladder Neoplasm
|
0.230 |
PosttranslationalModification
|
disease |
BEFREE |
p14 hypermethylation could be involved in early stage of bladder carcinogenesis, and p14 hypermethylation in pathologically normal urothelium samples should be considered a predictor of bladder cancer recurrence.
|
20800513 |
2012 |
|
Malignant neoplasm of urinary bladder
|
0.230 |
Biomarker
|
disease |
RGD |
Thirteen members of the S100 gene family were confirmed by real-time PCR to be differentially expressed in human bladder cancers, with overexpression of S100A2, S100A3, S100A5, S100A7, S100A8, S100A9, S100A14, S100A15, S100A16 and S100P, and underexpression of S100A1, S100A4 and S100B.
|
17970044 |
2007 |
|
Bladder Neoplasm
|
0.230 |
Biomarker
|
disease |
RGD |
Expression of S100 protein family members in the pathogenesis of bladder tumors.
|
17970044 |
2007 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
<b>Background:</b> Previous studies suggest S100A9 is a promising biomarker for prognosis in cancer, including hepatocellular carcinoma (HCC).
|
30719134 |
2019 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Our results indicate that expression of p14 FAST from an oncolytic HAdV can improve vector efficacy for the treatment of cancer.
|
31193718 |
2019 |
|
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Importantly, Co-expression of S100A8/S100A9 detected in 257 SCC specimens derived from five types of SCC tissues.
|
31208368 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Recent studies have suggested that S100A9 expression plays an important role during tumor development, progression and metastasis in various cancers.
|
31577709 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
cDNA analysis revealed an upregulation of S100A8 and S100A9 gene expression in melanoma metastases compared to primary melanomas.
|
31806053 |
2019 |