S100A10, S100 calcium binding protein A10, 6281

N. diseases: 150; N. variants: 2
Disease: Malabsorption Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024523
Disease: Malabsorption Syndrome
Malabsorption Syndrome 		0.010 Biomarker group BEFREE These data establish a novel host defense mechanism where LAMP-1 serves as a scaffold for both Siah-1 and p10 that allows the E3 ligase targeting p10 for ubiquitylation and degradation to suppress ARV infection.<b>IMPORTANCE</b> Avian reovirus (ARV) is an important poultry pathogen causing viral arthritis, chronic respiratory diseases, retarded growth, and malabsorption syndrome, leading to considerable economic losses to the poultry industry across the globe. 29321312 2018