S100B, S100 calcium binding protein B, 6285

N. diseases: 599; N. variants: 6
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.020 Biomarker disease BEFREE Certain S100 proteins, namely S100A4, the S100A8/S100A9 heterodimer and S100B, have been implicated in the pathophysiology of obesity-promoting macrophage-based inflammation via toll-like receptor 4 and/or receptor for advanced glycation end-products ligation. 31363816 2020
CUI: C0028754
Disease: Obesity
Obesity 		0.020 AlteredExpression disease BEFREE S100 calcium-binding protein B (S100B), a multifunctional macromolecule mainly expressed in nerve tissues and adipocytes, has been suggested to contribute to the pathogenesis of obesity. 28174179 2017