Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
MCP-1 expression in endothelial cells treated with uremic serum from ESRD patients with hypertension only was significantly increased compared with its expression in other cohorts.
|
31312972 |
2019 |
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Adiponectin receptor-1 and monocyte chemoattractant protein-1 mRNA expressions were significantly higher in visceral but not in subcutaneous adipose tissue of the ESRD group.
|
19539174 |
2009 |
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Osthole treatment significantly attenuated the protein expression of transforming growth factor‑β1 (TGF‑β1), reduced monocyte chemoattractant protein‑1 activity and increased the phosphoinositide 3‑kinase (PI3K)/protein kinase B (Akt) ratio in CRF rats.
|
28765904 |
2017 |
Kidney Failure, Chronic
|
0.600 |
Therapeutic
|
disease |
RGD |
Sedentary CRF rats exhibited azotemia, hypertension, anemia, oxidative stress, activation of NF-kappaB and upregulations of reactive oxygen species-generating enzyme, NAD(P)H oxidase, MCP-1, cyclooxygenase-2 (COX-2), and PAI-1 in LV.
|
18797164 |
2009 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
LHGDN |
The aim of this study was to determine if measurements of urinary epidermal growth factor (EGF) and monocyte chemotactic peptide-1 (MCP-1), at the time of renal biopsy, were a predictor of end-stage renal disease (ESRD) in a cohort of 132 patients with biopsy-proven IgAN.
|
17943082 |
2008 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
CTD_human |
Adiponectin receptor-1 and monocyte chemoattractant protein-1 mRNA expressions were significantly higher in visceral but not in subcutaneous adipose tissue of the ESRD group.
|
19539174 |
2009 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
RGD |
Our findings indicate localized expression of MCP-1 in proximal tubular cells in the remnant kidney and suggest that MCP-1 in proximal tubular cells is involved in tubulointerstitial damage in chronic kidney failure associated with glomerular hypertension.
|
12080327 |
2002 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
BEFREE |
We showed that HDL from patients with ESRD has a lower anti-inflammatory potential by reduced inhibition of monocyte chemoattractant protein-1 formation in vascular smooth muscle cells.
|
22328092 |
2012 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
BEFREE |
This study was thus conducted to determine plasma MCAF in patients with ESRD.
|
8808219 |
1995 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
BEFREE |
Furthermore, H<sub>2</sub>S decreased the expression levels of tumor necrosis factor-α, interleukin (IL)-6, IL-10, and monocyte chemoattractant protein-1, as well as the protein levels of p50, p65, and p-p65 in the kidney of CRF rats.
|
28352125 |
2017 |
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
CTD_human |
Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.
|
19420110 |
2009 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Therefore, in this study, we aimed to investigate the effect of MCP-1 gene -2518 A>G promoter polymorphism in chronic renal failure (CRF) patients requiring long-term hemodialysis.
|
25655256 |
2015 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
There was no statistically significant difference in the distribution of MCP-1 genotypes between ESRD patients without CVD and healthy controls.
|
19014891 |
2008 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Four polymorphisms showed association with ESRD: rs1801275 in the interleukin 4 receptor (IL4R) gene (OR: 0.66 (95%CI = 0.46-0.95); p = 0.025; overdominant model), rs4586 in chemokine (C-C motif) ligand 2 (CCL2) gene (OR: 0.70 (95%CI = 0.54-0.90); p = 0.005; additive model), rs301640 located in an intergenic binding site for signal transducer and activator of transcription 4 (STAT4) (OR: 1.82 (95%CI = 1.17-2.83); p = 0.006; additive model) and rs7830 in the nitric oxide synthase 3 (NOS3) gene (OR: 1.31 (95%CI = 1.01-1.71); p = 0.043; additive model).
|
22817530 |
2012 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, there were no associations of MCP-1, CCR2 and RANTES promoter SNPs with diabetic ESRD in Korean population.
|
17728497 |
2007 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Most of these eleven genetic variants were involved in GPCR signaling and receptor binding pathways whereas four were involved in chronic kidney failure. rs833061 [OR 2.08 (95% CI 1.63-2.66)] in the VEGFA gene and rs3917887 [OR 2.04 (95% CI 1.64-2.54)] in the CCL2 gene showed the most significant association with the risk of diabetic nephropathy.
|
25280384 |
2014 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
MCP-1 -2518 GG genotype and G allele may increase the risk of progression to ESRD in T2D cases.
|
25154422 |
2015 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Comparison of the <i>MCP-1</i> gene polymorphism distribution in ESRD patients with various primary diseases leading to ESRD did not show any significant differences.
|
31847640 |
2019 |