CCL21, C-C motif chemokine ligand 21, 6366

N. diseases: 186; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.030 Biomarker disease BEFREE We thank Zhou and co-workers for their interest regarding our newly published manuscript on the role of CCL21 in pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc). 30281215 2018
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.030 AlteredExpression disease BEFREE CCL21 levels were higher in patients with SSc compared with controls and were elevated prior to the diagnosis of PAH. 29687634 2018
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.030 Biomarker disease BEFREE These results obtained through a large cohort of European Caucasian SSc patients do not support the implication of CCL21, CD244 and CDK6 genes in the pathogenesis of SSc although these genes were recently identified as RA susceptibility genes. 21586211 2011