CCL22, C-C motif chemokine ligand 22, 6367

N. diseases: 182; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 AlteredExpression phenotype BEFREE Our results showed, reduction in MMP-2 (p=0.08), MMP-9 (p=0.03), CCL22 (p=0.003) and TGFβ1 (p=0.1) gene expression and Tregs frequency (p=0.01) which play a main role in the development of chronic inflammation, angiogenesis, tumorigenesis and metastasis. 30848576 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 AlteredExpression phenotype BEFREE CCL22 levels in sera have a predictive value for gastric cancer peritoneal metastasis and the early recurrence. 28501127 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 AlteredExpression phenotype BEFREE In the mouse SCCVII in vivo model, CCR4(+) cancer cells, but not CCR4(-) cells, metastasized to lymph nodes which contained CCL22 producing M2-like macrophages. 23180648 2013