CX3CL1, C-X3-C motif chemokine ligand 1, 6376

N. diseases: 243; N. variants: 6
Disease: Coronary Artery Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.040 GeneticVariation disease BEFREE Compared with their corresponding wild-type genotypes, CX3CL1 rs170364 and CX3CR1 rs17793056 were associated with increased susceptibility to CAD. 25845619 2015
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.040 GeneticVariation disease BEFREE CC genotype and C allele in rs614230 (CX3CL1) were significantly related with decreased risk of CAD (OR=0.38, 95% CI=0.17-0.86; OR=0.66, 95% CI=0.45-0.97).For IL-6 rs2066992 polymorphism. 26191329 2015
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.040 GeneticVariation disease BEFREE The CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma. 20523302 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.040 Biomarker disease LHGDN Our results suggest that the CX3CL1/CX3CR1 dyad may contribute to atherogenesis and plaque destabilization in human CAD. 16224053 2005
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.040 Biomarker disease BEFREE Our results suggest that the CX3CL1/CX3CR1 dyad may contribute to atherogenesis and plaque destabilization in human CAD. 16224053 2005