BCAN, brevican, 63827

N. diseases: 25; N. variants: 2
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression disease BEFREE Brevican, an important extracellular proteoglycan that is upregulated in glioblastomas, can be degraded by certain proteases. 16003758 2006
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression disease BEFREE These results demonstrate for the first time that ADAMTS-5 is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 may play a role in glioma cell invasion through the cleavage of brevican. 16133547 2005
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression disease LHGDN These results demonstrate for the first time that ADAMTS-5 is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 may play a role in glioma cell invasion through the cleavage of brevican. 16133547 2005