CXCL12, C-X-C motif chemokine ligand 12, 6387

N. diseases: 626; N. variants: 21
Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.030 Biomarker disease BEFREE <b>Conclusion:</b> SDF-1 is an independent predictor of all-cause mortality and major adverse cardiovascular and cerebrovascular events in long-term follow-up of patients with ACS and adds prognostic information beyond traditional cardiovascular risks factors. 31559838 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.030 AlteredExpression disease BEFREE The relative increase in circulating CD34+ cells and the low SDF-1 levels observed following rHDL infusions in ACS patients point towards a role of rHDL in cardiovascular repair mechanisms. 28060837 2017
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.030 Biomarker disease BEFREE Patients with ACS presented with enhanced platelet-bound-SDF-1 compared with SAP. 22044645 2012