UBE2O, ubiquitin conjugating enzyme E2 O, 63893

N. diseases: 19; N. variants: 3
Disease: Tumor Initiation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.010 GeneticVariation phenotype BEFREE Here we show that Ube2o deletion in MMTV-PyVT or TRAMP mice profoundly impairs tumor initiation, growth, and metastasis, while switching off the metabolic reprogramming of tumor cells. 28162974 2017