PRDM1, PR/SET domain 1, 639

N. diseases: 126; N. variants: 8
Disease: Lupus Erythematosus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.020 AlteredExpression disease BEFREE Blimp1 mRNA and protein expression levels and tissue distribution in the kidneys, spleen and lymph nodes of MRL/lpr lupus and normal mice were analyzed. 23911415 2013
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.020 GeneticVariation disease BEFREE Given that the murine lupus susceptibility locus Nba2 includes the IFN-regulated genes Ifi202 (encoding for the p202 protein), Aim2 (encoding for the Aim2 protein), and Fcgr2b (encoding for the FcγRIIB receptor), we investigated whether the IRF5/Blimp-1 axis could regulate the expression of these genes. 22116829 2012