|
Myocardial Infarction
|
0.290 |
AlteredExpression
|
disease |
BEFREE |
Acute myocardial infarction and ischemic stroke are associated with high platelet reactivity on clopidogrel in 6-58% of patients when assessed with P-selectin expression, and high reactivity was associated with an increased risk of recurrence after myocardial infarction.
|
29667460 |
2018 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
In order to find new informative predictors of myocardial infarction, we performed an analysis of genotype frequencies of polymorphic markers of SELE (rs2076059, 3832T > C), SELP (rs6131, S290 N), SELL (rs1131498, rs1131498" genes_norm="6402">F206L), ICAM1 (rs5498, K469E), VCAM1 (rs3917010, c.928 + 420A > C), PECAM1 (rs668, V125L), VEGFA (rs35569394, -2549(18)I/D), CCL2 (rs1024611, -2518A > G), NOS3 (rs1799983, E298D), and DDAH1 (rs669173, c.303 + 30998A > G) genes in the group of Russian men with myocardial infarction (N = 315) and the control group of corresponding ethnicity, gender, and age (N = 286).
|
26662939 |
2016 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
The effect of SELE and SELP genetic polymorphisms on the pathogenesis of MI was investigated in this meta-analysis with a total of ten case-control studies, including 2,696 MI patients and 4,724 healthy subjects.
|
24639176 |
2014 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
However, we observed no significant associations between SELP genetic polymorphisms and the risk of CHD and MI among Africans.
|
24504449 |
2014 |
|
Myocardial Infarction
|
0.290 |
Biomarker
|
disease |
RGD |
In conclusion, in a rat model of myocardial infarction, the thrombosis, inflammatory reaction and tissue damage-related indicators GMP-140, hs-CRP, IL-6 and MMP-9 increased significantly, while t-PA and TIMP-1 decreased dynamically.
|
21567088 |
2011 |
|
Myocardial Infarction
|
0.290 |
Biomarker
|
disease |
LHGDN |
Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions.
|
17488661 |
2007 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
We illustrate the method with three applications on the relationship between (1). the P-selectin gene and myocardial infarction, (2). the cholesteryl ester transfer protein gene and plasma high-density-lipoprotein cholesterol concentration, and (3). genes of the renin-angiotensin-aldosterone system and myocardial infarction.
|
12902385 |
2003 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
Specific haplotypes of the P-selectin gene are associated with myocardial infarction.
|
12165563 |
2002 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
LHGDN |
Specific haplotypes of the P-selectin gene are associated with myocardial infarction.
|
12165563 |
2002 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
The ECTIM (étude cas-temoin de l'infarctus myocarde) extension study was established to determine whether a previously implicated polymorphism of the P-selectin gene was associated with myocardial infarction risk in men and women in Belfast and Glasgow.
|
11040019 |
2000 |
|
Myocardial Infarction
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |