Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections
0.050 GeneticVariation group BEFREE Genetic variants in the autophagy-related genes NOD2, PARK2 and ATG16L1 has been associated with susceptibility to mycobacterial diseases. 27128681 2016
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections
0.050 GeneticVariation group BEFREE As NOD2 polymorphisms are associated with Crohn's disease (CD), a link has been suggested between mycobacterial infections and CD. 25335775 2015
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections
0.050 Biomarker group BEFREE Some IBD associated genes are involved in innate immunity, in the autophagy and in the inflammatory response such as NOD2, ATG16L1 and IL23R, while other are implicated in immune mediated disease (STAT3) and in susceptibility to mycobacterium infection (IL12B). 26604638 2015
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections
0.050 Biomarker group BEFREE Recently, Nod2 has been also shown to be exquisitely tuned to detect mycobacterial infections and mount a protective immunity against these pathogens. 20643110 2010
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections
0.050 Biomarker group BEFREE In this review, we discuss the current understanding of mycobacterial and Crohn's genetic susceptibility and review the evidence that NOD2/CARD15 may mediate host resistance to mycobacterial infection. 17012971 2006