Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.050 Biomarker group BEFREE Here, we showed that NOD2 suppressed FMDV replication during viral infection. 30894473 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.050 Biomarker group BEFREE These findings prompted us to further investigate whether NOD2 receptor may contribute to regulate inflammation during viral infection. 29445379 2018
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.050 Biomarker group BEFREE Regulatory NLRs that augment pro-inflammatory pathways include nucleotide-binding oligomerization domain-containing protein 1 (NOD1) and NOD2, which have been shown to form a multiprotein complex termed the NODosome that significantly modulates IFN and NF-κB signalling following viral infection. 26763980 2016
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.050 Biomarker group BEFREE NLRC2 is an important activator of innate antiviral signaling and was recently found to mitigate inflammation during virus infection through autophagy. 23947344 2013
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.050 GeneticVariation group BEFREE In addition, NDV infection tended to lower the variance in AI among DC populations for the NOD2 gene (p=0.05), but not the ATG16L1 gene (p=0.32). 23850724 2013