POTEM, POTE ankyrin domain family member M, 641455

N. diseases: 133; N. variants: 1
Disease: Sleeplessness ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0917801
Disease: Sleeplessness
Sleeplessness 		0.030 Biomarker phenotype BEFREE ACT-541468 in elderly subjects was well tolerated and pharmacokinetics and pharmacodynamics are compatible with a drug for the treatment of insomnia.Clinicaltrials.gov: NCT02571855. 31642731 2020
CUI: C0917801
Disease: Sleeplessness
Sleeplessness 		0.030 Biomarker phenotype BEFREE In conclusion, multiple-dose PK/PD of ACT-541468 were compatible with a drug designated to treat insomnia. 31221502 2019
CUI: C0917801
Disease: Sleeplessness
Sleeplessness 		0.030 Biomarker phenotype BEFREE ACT-541468 is a novel dual orexin receptor antagonist (DORA) under development for the treatment of insomnia. 30284597 2019