SOX17, SRY-box transcription factor 17, 64321

N. diseases: 113; N. variants: 2
Disease: Malignant neoplasm of esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.030 AlteredExpression disease BEFREE SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes. 30777052 2019
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.030 AlteredExpression disease BEFREE Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression. 24407731 2014
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.030 AlteredExpression disease BEFREE Loss of SOX17 expression is correlated to promoter region hypermethylation, and re-expression was activated by 5-aza-2'-deoxycytidine treatment in esophageal cancer cell lines. 22921431 2012