SOX17, SRY-box transcription factor 17, 64321

N. diseases: 113; N. variants: 2
Disease: Tumor Angiogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.020 Biomarker phenotype BEFREE Furthermore, endothelial Sox17 ablation rescues vascular network from excessive tip cell formation and hyperbranching under Notch inhibition in developmental and tumor angiogenesis. 24755984 2014
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.020 AlteredExpression phenotype BEFREE Whereas overexpression of Sox17 in tECs promoted tumor angiogenesis and vascular abnormalities, Sox17 deletion in tECs reduced tumor angiogenesis and normalized tumor vessels, inhibiting tumor growth. 23241958 2013