HHIP, hedgehog interacting protein, 64399

N. diseases: 122; N. variants: 16
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.040 Biomarker group BEFREE TGFβ1 shares the similar staining pattern as Hhip in human DM kidneys. 31794697 2020
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.040 Biomarker group BEFREE The association between the Hhip and the presence of diabetes was examined by a multivariate linear regression analysis. 31590446 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.040 AlteredExpression group BEFREE Thus, our studies demonstrated that renal Hhip expression is associated with nephropathy development in diabetes and that hyperglycemia-induced renal Hhip expression may mediate glomerular endothelial fibrosis and apoptosis in diabetes, a novel finding. 29654303 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.040 Biomarker group BEFREE HIP rats develop diabetes between 5 and 10 months of age, characterized by an approximately 60% deficit in beta-cell mass that is due to an increased frequency of beta-cell apoptosis. 15161755 2004