SFTPC, surfactant protein C, 6440

N. diseases: 89; N. variants: 11
Disease: Respiratory morbidity ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1301752
Disease: Respiratory morbidity
Respiratory morbidity 		0.010 AlteredExpression disease BEFREE SNPs in several genes were associated with increased chronic respiratory morbidity (interleukin 10 (IL10), nitric oxide synthase 2A (NOS2A), surfactant protein C (SFTPC), matrix metalloproteinase 16 (MMP16) and vitamin D receptor (VDR)) and reduced lung function at 1 year (MMP16, NOS2A, SFTPC and VDR) in infants who had had RSV LRTIs. 24487983 2014