SFTPD, surfactant protein D, 6441

N. diseases: 194; N. variants: 12
Disease: Eosinophilia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.020 AlteredExpression disease BEFREE O<sub>3</sub> induced significant BAL fluid neutrophilia and eosinophilia and increased AHR and expression of IL6 and IL25 mRNA in the airway epithelium together with increased BAL fluid group 2 innate lymphoid cell (ILC2s), CD1c<sup>+</sup> myeloid dendritic cell, and CD4<sup>+</sup> T-cell counts and diminished surfactant protein D expression. 31627909 2020
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.020 AlteredExpression disease BEFREE Combined allergic airway sensitization and O<sub>3</sub> exposure heightened eosinophilia and nos2 mRNA (iNOS) activation in the lung tissue and S-nitrosylation related de-oligomerisation of SP-D in the airways. 29733456 2018