The RLPD-group scored significantly lower than the ACL-group for the three KOOS subscales "Pain" (73.6 vs. 79.8, p < 0.05), "Symptoms" (71.7 vs. 79.3, p < 0.05) and "ADL" (84.7 vs 89.5, p < 0.05).
We found no significant average treatment effect on the treated (ATT) of working to age 66 or above on the outcomes, measured an average of 12 years after retirement: mortality (ATT -0.039), the ability to climb stairs (ATT -0.023), self-rated health (ATT -0.009), ADL limitations (ATT -0.023), or musculoskeletal pain (ATT -0.009) in late life.
Patients with neural compression scored significantly higher in the domain of pain and patients requiring assistive devices for ambulation scored significantly higher in the domains of ADL and social functions.
The range in differences between the 2-year change in individual PROMs were as follows: HOOS pain (0.6-2.4), HOOS symptoms (0-3.8), HOOS ADL (0.4-4), and HOOS QOL (0.5-3.6).
Interventions addressing physical functioning or fatigue and pain might contribute to enhancing ADL ability and HRQoL among people with advanced cancer.
First, we applied a hierarchical cluster analysis and the principal component analysis (PCA) to a panel of questionnaires [comorbidity (Charlson, CIRS), clinical stability (MEWS), social frailty (Flugelman), cognitive dysfunction (SPSMQ), depression (5-item GDS), functional dependence (ADL, IADL, Barthel), risk of sore threats (Exton-Smith scale), nutrition (MNA), pain (NRPS), adherence to therapy (Morisky scale)], in order to select domains informative for the definition of complexity.
Age, education, pain, falls, household not fully adapted for one's needs, using assistive devices, lack of satisfaction with life, and low assessment of quality of life had a significant impact on the prevalence of ADL and/or IADL disabilities in the elderly inhabitants of rural areas.
SHOMRI total scores correlated with intraoperative femoral cartilage grade (ρ = 0.42; p = 0.002), acetabular cartilage grade (ρ = 0.30; p = 0.046), and labral tear grade (ρ = 0.42; p = 0.003) as well as with preoperative Tönnis grade (ρ = 0.37, p = 0.013), HOOS pain score (ρ = -0.33; p = 0.039), HOOS ADL score (ρ = -0.39; p = 0.007), and HOOS sports score (ρ = -0.30; p = 0.037).
In the total sample, 12 of the 20 independent variables were significantly associated with LS: need of help with ADL; walking difficulties; number of non-motor symptoms (NMS); fatigue; depressive symptoms; general self-efficacy; motor symptoms; pain; PD severity; freezing episodes; gender (woman); and fluctuations.