DCLRE1C, DNA cross-link repair 1C, 64421

N. diseases: 150; N. variants: 15
Disease: Childhood Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 GeneticVariation disease BEFREE Mutations in the NHEJ factor ARTEMIS cause radiation-sensitive severe combined immunodeficiency in humans and may increase susceptibility to lymphoma in some settings. 17384673 2007
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 Biomarker disease BEFREE Significant in vivo therapeutic efficacy was demonstrated in a SCID mouse xenograft leukemia/lymphoma model. 17440052 2007
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 Biomarker disease BEFREE Cytokine-induced killer (CIK) cells have been shown to eradicate established tumors in a SCID mouse-human lymphoma model. 9536262 1998