SHBG, sex hormone binding globulin, 6462

N. diseases: 368; N. variants: 20
Disease: Hypothyroidism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.030 Biomarker disease BEFREE SHBG was significantly lower in HypoHT (45.417.4 nmol/L) compared with HS (60.0919.51 nmol/L, p < 0.05). 31681972 2020
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.030 Biomarker disease BEFREE Taken together these data suggest low SHBG is a marker of abdominal obesity and increased serum triglycerides, conditions which are known to have been associated with low testosterone and low T4. 29995902 2018
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.030 AlteredExpression disease BEFREE Sex hormone-binding globulin (SHBG) levels in serum are affected by thyroid status; hyperthyroidism is associated with high SHBG levels, whereas hypothyroid patients have low or normal SHBG levels. 3084540 1986